Which is incorrect with reference to the transforming principle ?

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S strain $\to$ Inject into mice $\to$ Mice die

R strain $\to$ Inject into mice $\to$ Mice live

S strain (heat killed) $\to$ Inject into mice $\to$ Mice live

S strain(heat killed) + R strain(live) $\to$ Inject into mice $\to$ Mice live

answer is D.

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Detailed Solution

Griffith injected mice with a mixture of the heat-killed S strain and live R strain bacteria. Surprisingly, the mice injected with this mixture of heat-killed S strain and live R strain bacteria died. This was unexpected because, individually, neither the heat-killed S strain nor the live R strain was lethal to the mice.

The significance of this experiment was that it demonstrated a phenomenon called "transformation." Something from the heat-killed S strain (now known to be DNA) had transformed the harmless R strain into a pathogenic form. This provided strong evidence that DNA carries the genetic information responsible for an organism's characteristics. This groundbreaking experiment paved the way for the discovery of the structure and function of DNA and its role in heredity and genetics.

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