Q.

Which of the following amides are more reactive than benzamide  (C6H5CONH2) towards Hoffmann bromamide reaction?

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a

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b

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c

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d

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answer is A, B.

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Detailed Solution

electron releasing group at aryl ring stabilizes the transition state and rate of reaction increases whereas electron withdrawing groups like -NO2 and -Cl destabilizes the transition state and hence rate of reaction decreases. Hence, option A and option B are more reactive.

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