Q.

Which of the following are intermediates (A) in the Hofmann degradation reaction?

RCONH2BrKOHAwaterRNH2

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a

RNCO 

b

RNH2 

c

All of the above 

d

RCONHBr 

answer is A, Û, B.

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Detailed Solution

In the  Hofmann bromamide degradation reaction, the intermediates are RCONHBr and  RNCO.
In this reaction an amide is heated with bromine and caustic soda to give primary amine, Thus amide group is converted to amine group. In this reaction, one carbon atom is lost as carbonate ion.

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