Q.

Which of the following compound (s) fail in Friedel-Crafts alkylation reaction?

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a

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b

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c

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d

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answer is B, C.

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Detailed Solution

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Fredel craft alkylation is very slow reaction. It fail to occur at strongly deactivated ring like nitro benzene. In case of aniline, AlCl3 react with –NH2 forming a salt, which is highly deactivated.

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Which of the following compound (s) fail in Friedel-Crafts alkylation reaction?