Q.

Which of the following couples are most likely to give birth to a haemophilic daughter?

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a

A homozygous normal woman and a haemophilic man 

b

A normal woman and a normal man

c

A haemophilic woman and a normal man

d

A carrier woman and a haemophilic man

answer is B.

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Detailed Solution

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If the woman is carrier (XXh) and her husband is haemophilic (XhY), half of her daughters would be haemophilic (XhXh) and the other half would be carriers (XXh).
If the woman is haemophilic (XhXh) and her husband is normal (XY), all the daughters would be carriers (XXh).
If the woman is homozygous normal (XX) and her husband is haemophilic (XhY), all the daughters would be carriers (XXh).
If the woman is homozygous normal (XX) and her husband is normal (XY), all the daughters would be normal (XX).

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Which of the following couples are most likely to give birth to a haemophilic daughter?