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Q.

Which of the following does not shift the oxyhemoglobin dissociation curve to the right?

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a

increased carbon dioxide 

b

increased pH

c

increased temperature

d

increased 2, 3-DPG

answer is B.

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Detailed Solution

Concept: The proportion of hemoglobin in its saturated state on the vertical axis is plotted against the average oxygen tension on the horizontal axis to generate the oxygen–hemoglobin dissociation curve.

The standard curve moves to the left when pH increase (increase in H+ ion concentration), and to the right when pH decreases.

With acidosis, the oxyhemoglobin dissociation curve shifts to the right, which facilitates the unloading of oxygen at the tissues, increasing oxygen delivery.
 

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