Which of the following enzymes are used as a marker for the lysosomes?
(a) Phospholipase
(b) Acid phosphatase
(c) Pyruvate dehydrogenase
(d) Succinate dehydrogenase

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Detailed Solution

(b) Acid phosphatase

Acid phosphatase is the primary enzyme used as a marker for lysosomes.¹

Lysosomes are filled with a variety of digestive enzymes known as acid hydrolases, which function best in the acidic environment of the organelle.²Acid phosphatase is one of the most abundant and consistently present of these enzymes, making it a reliable biochemical marker for identifying the presence of lysosomes in cell studies.³

The other options are incorrect as they are markers for different parts of the cell:

Phospholipase is a general type of enzyme not specific to lysosomes.
Pyruvate dehydrogenase and Succinate dehydrogenase are key enzymes in cellular respiration and are used as markers for the mitochondria.⁴

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