Which of the following factors does not cause a rightward shift in the oxyhemoglobin dissociation curve?

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Increased carbon dioxide

Increased pH

Increased temperature

Decreased 2, 3-DPG

answer is D.

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Detailed Solution

The oxyhemoglobin dissociation curve shows the relationship between the partial pressure of oxygen and the percentage saturation of hemoglobin with oxygen.

Factors that cause a rightward shift in the curve promote the release of oxygen to the tissues, while factors that cause a leftward shift promote the binding of oxygen to hemoglobin.

Increased carbon dioxide, increased temperature, and increased 2,3-DPG levels all cause a rightward shift in the curve, indicating that hemoglobin is more likely to release oxygen to the tissues. Conversely, increased pH (or decreased H+ ion concentration) causes a leftward shift, indicating that hemoglobin is more likely to bind oxygen.

Therefore, decreased 2, 3-DPG will not cause a rightward shift in the oxyhemoglobin dissociation curve.

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