Q.

Which of the following factors influence the affinity with which the haemoglobin binds to oxygen?

(a) Acidity (pH)

(b) Temperature

(c) Partial pressure of carbon dioxide

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a

(a), (b) and (c)

b

Only (b) and (c)

c

Only (a) and (c)

d

Only (a) and (b)

answer is D.

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Detailed Solution

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The most important factor that determines how much O2 binds to hemoglobin is the pO2. Several other factors influence the tightness or affinity with which hemoglobin binds O2 - Temperature, pH, pCO2, and BPG (2,3-bisphosphoglycerate).

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