Which of the following features are common to both peptide hormones and steroid hormones?
A. Transported to target tissues through the blood.
B. Bind to hormone receptors inside the target cells.
C. Hormone receptors are made up of proteins.
D. Generate second messengers inside the target cells.
E. Can trigger a response if injected directly into the cytoplasm of the target cell.

A. Endocrine hormones are produced by ductless glands and released and are transported to a target organs through the blood.
C. Hormone receptors of all the hormones are specific proteins located in the target tissues.
B. Water-soluble hormones bind to membrane bound receptors.
D. Second messenger is generated only in case of water-soluble hormones.
E. Because receptors for water-soluble hormones are located on the cell surface, facing the extracellular space, injecting the hormone into the cytoplasm would not trigger a response.