Q.

Which of the following hormones is not transported from the hypothalamus to the pituitary through the hypophyseal portal vein?

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a

GnRH

b

GHRH

c

ADH

d

GHIH

answer is C.

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Detailed Solution

From the hypothalamus, ADH and oxytocin are transported through the axons of the hypothalamo-hypophyseal tract to the neurohypophysis.

The releasing hormones and inhibiting hormones secreted by the hypothalamus reach the adenohypophysis through the hypophyseal portal system. These hormones include:

  • Gonadotropin-releasing hormone (GnRH)
  • Growth hormone-releasing hormone (GHRH) or somatocrinin
  • Thyrotropin-releasing hormone (TRH) 
  • Corticotropin-releasing hormone (CRH) 
  • Prolactin-releasing hormone (PRH) 
  • Growth hormone-inhibiting hormone (GHIH) or somatostatin.
  • Prolactin-inhibiting hormone (PIH) or dopamine.
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