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Which of the following hormones leads to the generation of cyclic AMP in its target cells?

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Thyroxine

Thyrocalcitonin

Estradiol

Cortisol

answer is B.

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Detailed Solution

Thyrocalcitonin is a water-soluble (peptide) hormone and binds to membrane-bound receptors and leads to the generation of a second messenger (cyclic AMP) inside the target cells.

For example, it inhibits the activity of osteoclasts.

Thyroxine, cortisol and estradiol (estrogen) are lipid-soluble hormones and enter the target cells.

They bind to intracellular receptors and influence gene expression.

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