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Q.

Which of the following is an example of a point mutation?

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a

Sickle cell anemia

b

Chromosomal aberration

c

Frame-shift mutation

d

DNA supercoiling

answer is A.

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Detailed Solution

Sickle cell anemia is an example of point mutation. It is caused by the change in single base pair. Glutamic acid is replaced by valine at the sixth position of the beta globin chain in the haemoglobin molecule.

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Which of the following is an example of a point mutation?