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Q.

Which of the following is incorrect about counter-current mechanism?

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a

The flow of filtrate in two limbs of vasa recta is in opposite direction.

b

The flow of blood in two limbs of vasa recta is also in opposite direction.

c

NaCI is transported by the ascending limb of HL which is exchanged with the descending limb of vasa recta.
 

d

NaCI is returned to in interstitium by the ascending portion of vasa recta.

answer is A.

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Detailed Solution

Mammals have the ability to produce a concentrated urine. The Henle’s loop and vasa recta play a significant role in this. The flow of filtrate in the two limbs of Henle’s loop is in opposite directions and thus forms a counter current. The flow of blood through the two limbs of vasa recta is also in a counter current pattern. The proximity between the Henle’s loop and vasa recta, as well as the counter current in them help in maintaining an increasing osmolarity towards the inner medullary interstitium, i.e., from 300 mOsmolL–1 in the cortex to about 1200 mOsmolL–1 in the inner medulla. This gradient is mainly caused by NaCl and urea. NaCl is transported by the ascending limb of Henle’s loop which is exchanged with the descending limb of vasa recta. NaCl is returned to the interstitium by the ascending portion of vasa recta. Similarly, small amounts of urea enter the thin segment of the ascending limb of Henle’s loop which is transported back to the interstitium by the collecting tubule.

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