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Q.

Which of the following is not a function of insulin?

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a

Stimulation of gluconeogenesis in hepatocytes

b

Uptake of glucose by adipocytes

c

Conversion of glucose into glycogen

d

Uptake of glucose by hepatocytes

answer is D.

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Detailed Solution

Gluconeogenesis in hepatocytes is stimulated by glucagon. 

Insulin acts mainly on hepatocytes and adipocytes (cells of adipose tissue), and enhances cellular glucose uptake and utilisation. As a result, there is a rapid movement of glucose from blood to hepatocytes and adipocytes resulting in decreased blood glucose levels (hypoglycemia). Insulin also stimulates conversion of glucose to glycogen (glycogenesis) in the target cells.

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