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Q.

Which of the following is not a genetic disorder of blood?

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a

Cystic fibrosis

b

Thalassemia 

c

Sickle cell anaemia 

d

Haemophilia 

answer is D.

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Detailed Solution

  • Cystic Fibrosis (CF):

A genetic disorder affecting the respiratory and digestive systems.
Causes thick and sticky mucus in the airways and organs.
Symptoms include lung infections, difficulty breathing, and digestive problems.
Inherited as an autosomal recessive trait.

  • Haemophilia:

A group of bleeding disorders, primarily affecting males.
Results from a deficiency in blood clotting factors.
Causes prolonged bleeding after injury or surgery.
Inherited as an X-linked recessive trait.

  • Sickle Cell Anemia:

A blood disorder characterised by abnormal, sickle-shaped red blood cells.
Leads to pain, anemia, and organ damage.
Caused by mutations in the HBB gene.
Inherited as an autosomal recessive trait.

  • Thalassemia:

A group of blood disorders resulting in reduced or absent hemoglobin production.
Includes alpha and beta thalassemia.
Symptoms include anemia, fatigue, and pale skin.
Inherited in an autosomal recessive manner.

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