Which of the following is not responsible for concentrating urine?

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Reabsorption of water from the ascending limb of the Henle’s loop

Countercurrent flow of blood in the vasa recta

Countercurrent flow of the filtrate in the Henle’s loop

Maintenance of hyperosmolarity towards inner medullary interstitium

answer is A.

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Detailed Solution

The ascending limb of the loop of Henle is impermeable to water. Water is reabsorbed from the descending limb of the loop of Henle.

The proximity between the Henle’s loop and vasa recta, as well as the counter current in them help in maintaining an increasing osmolarity towards the inner medullary interstitium, i.e., from 300 mOsmolL^–1 in the cortex to about 1200 mOsmolL^–1 in the inner medulla. Presence of such interstitial gradient helps in an easy passage of water from the collecting tubule thereby concentrating the filtrate (urine).

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