Which of the following is the main reason for the unstable nature of RNA?

see full answer

Talk to JEE/NEET 2025 Toppers - Learn What Actually Works!

Real Strategies. Real People. Real Success Stories - Just 1 call away

An Intiative by Sri Chaitanya

2'-OH on terminal nucleotide only

5'-OH at every nucleotide

1'- OH at every nucleotide

2'-OH group present at every nucleotide in RNA

answer is D.

(Unlock A.I Detailed Solution for FREE)

Ready to Test Your Skills?

Check your Performance Today with our Free Mock Test used by Toppers!

Take Free Test

Detailed Solution

The 2'-OH group in RNA's ribose sugar is chemically active. It can participate in various chemical reactions, including hydrolysis (the breakdown of chemical bonds by water). This makes RNA more susceptible to hydrolytic cleavage, leading to its relatively rapid degradation under certain conditions, especially in the presence of water or specific enzymes.

Watch 3-min video & get full concept clarity

Result Producing online coaching for JEE/NEET of south India

Largest All India Test Series for JEE/NEET

Best Books for IIT JEE

Best Books for NEET

How to Join IIT after 10th