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Q.

Which of the following is the most likely explanation for hypothyroidism in a patient whose iodine level is normal?

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a

Hypersecretion of TRH

b

Hyposecretion of TSH

c

Hypersecretion of TSH

d

Hyposecretion of TCT

answer is B.

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Detailed Solution

TRH is produced by the hypothalamus and stimulates the synthesis of TSH by adenohypophysis. TSH stimulates the synthesis and secretion of thyroid hormones from the thyroid gland. Hyposecretion of TSH can cause hypothyroidism, in spite of normal levels of iodine.

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