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Q.

Which of the following reactant will show inertness to nucleophilic substitution reaction ?

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a

AII the above

b

Ph - Br

c

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d

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answer is D.

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Detailed Solution

SN1 and SN2 not possible in the following.
 

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Stearically crowded reaction center for SN2 Bridgehead Csp2 hybridized not possible (Bredt's rule). Hence SN1 and SN2 not possible.

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Lone pair of Br in resonance with Benzene ring. Hence partial double bond character. No SN1 or SN2 possible.
 

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not stable. Hence SN1 not possible stearic crowded for backside attack. Hence SN2 not possible.

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