Q.

Which of the following statements about Griffith’s experiment are correct ?       

  I) S- strain have capsule                                       

 II) Mouse will die if injected with living S-strain

III) Mouse will die if injected with living R-strain                                    

 IV) Transforming principle is associated with genetic material of R-strain

 V) Transformation of R-strain into S-strain can take place in a test tube

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a

III and IV

b

III, IV and V

c

I, II and V

d

I and II

answer is B.

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Detailed Solution

Griffith concluded that S-strain bacteria have a mucous coat, while R-strain does not. Mice infected with the S-strain (virulent) die from pneumonia infection, but mice infected with the R-strain do not develop pneumonia. When he injected a mixture of heat killed S-strand and live R-bacteria, the mice died.

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