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Which of the following statements are correct about thalassemia?
A. The defect could be either due to genemutation or deletion.
B. Alpha thalassemia is controlled by two closely linked genes HBA1 and HBA2.
C. Beta thalassemia is controlled by a single gene HBB on chromosome 16.
D. Beta thalassemia is a qualitative problem of synthesising an incorrectly functioning globin.

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C and D only

B and D only

A and B only

B and C only

answer is A.

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Detailed Solution

Thalassemia:

The defect could be either due to gene mutation or deletion.
Alpha thalassemia is controlled by two closely linked genes HBA1 and HBA2.
Beta thalassemia is controlled by a single gene HBB on chromosome 11.
Beta thalassemia is a quantitative problem of synthesising too few globins.

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