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Q.

Which of the following statements are true regarding the proximal convoluted tubule of the human nephron? 
(A) It is lined by columnar epithelium.
(B) It is situated in the medullary region of the kidney.
(C) It secretes H+ ions into the filtrate.
(D) Conditional reabsorption of Na+ aided by aldosterone occurs in it.
(E) 70 to 80% of water and electrolyte reabsorption occur in it.

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a

A, E   

b

B, D 

c

C, E 

d

A, C 

answer is A.

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Detailed Solution

PCT is lined by cuboidal epithelium with brush border.  Conditional reabsorption is regulated by hormones (aldosterone, ADH) which act on DCT and collecting duct, PCT, DCT and Bowman’s capsule are in renal cortex. 

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