Which of the following statements includes critical research areas in biotechnology?

(A) Downstream processing
(B) Creating optimal conditions through engineering for a catalyst to act  
(C) Providing the best catalyst in the form of improved organism usually a microbe or pure enzyme 

Three critical research areas of biotechnology are:
(i) Providing the best catalyst in the form of improved organism usually a microbe or pure enzyme.
(ii) Creating optimal conditions through engineering for a catalyst to act, and
(iii) Downstream processing technologies to purify the protein/organic compound.