Which of the following statements is correct?

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Francis Crick proposed the Reverse Central dogma in molecular biology.

The pitch of the helix is 3.4 mm

The ratios between Adenine and Thymine, and Guanine and Cytosine varies from one organism to another.

Two nucleotides are linked through 3'-5' phosphodiester linkage to form a dinucleotide.

answer is D.

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Detailed Solution

When a phosphate group is linked to OH of 5' C of a nucleoside through phosphodiester linkage, a corresponding nucleotide (or deoxynucleotide depending upon the type of sugar present) is formed. Two nucleotides are linked through 3'-5' phosphodiester linkage to form a dinucleotide. Two nucleotides are linked through 3'-5' phosphodiester linkage to form a dinucleotide.

Francis Crick proposed the Central dogma in molecular biology.