Which of the following statements is not true ?

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Descending limb of loop of Henle is impermeable to solutes.

Distal convoluted tubule functions in $K^{+}, {Na}^{+}$ homeostasis

Descending limb of loop of Henle is impermeable to water.

Loop of Henle is largely responsible for concentrated urine

answer is C.

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Detailed Solution

The descending limb of loop of Henle is permeable to water.

(1) The descending limb of loop of Henle is almost impermeable to electrolytes (not totally impermeable).

(2) The distal convoluted tubule (DCT) regulates K⁺ and Na⁺ homeostasis by fine-tuning the reabsorption of sodium
and the secretion of potassium. By actively secreting potassium, the DCT helps maintain appropriate levels of potassium in the body, which is crucial for proper cell function, nerve transmission and muscle contraction.

(4) The loop of Henle is primarily responsible for concentrating urine by creating a concentration gradient in the kidney
medulla through the reabsorption of water and solutes, by acting as a countercurrent multiplier.

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