Q.

Which of the following statements regarding the structure of pro-insulin and mature insulin is/are incorrect?
(i) Pro-insulin is made up of three polypeptide chains.
(ii) C-polypeptide chain with 33 amino acids is removed prior to insulin formation.
(iii) Mature insulin is made up of 51 amino acids arranged in two polypeptide chains.
(iv) Polypeptide chain A has 30 amino acids and polypeptide chain B has 21 amino acids
(v) Polypeptide chains A and B are interconnected by only one S-S linkage.
 

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a

(i) and (ii)

b

(iii) and (iv)

c

(iv) and (v)

d

(iii), (iv) and (v)

answer is C.

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Detailed Solution

Polypeptide chain A has 21 amino acids and polypeptide chain B has 30 amino acids.

Polypeptides A and B are interconnected by two S-S linkages.

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