Which of the following switching ligands or rotating Fischer structures changes its absolute configuration?

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An even number of switches

Rotating the Fischer projection by 180° in the plane of the paper

An odd number of switches

Exchange ligands across the horizontal bond as well as those across the vertical bond

answer is B.

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Detailed Solution

A Fischer projection or Fischer projection formula is a convention used to depict a stereoformula in two dimension without destroying the stereochemical information, i.e., absolute configuration, at chiral centers. Step 2: Push the two bonds coming out of the plane of the paper onto the plane of the paper.

An even number of switches does not change absolute configuration.

An odd number of switches does change absolute configuration.

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