Which of the following will not increase urine output?

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Decreased secretion of angiotensin converting enzyme (ACE)

Increased secretion of ANF

Decreased secretion of ADH

Increased secretion of renin

answer is B.

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Detailed Solution

ACE is an enzyme involved in the production of angiotensin II, which promotes water reabsorption in the kidneys and decreases urine output. Therefore, decreasing ACE activity leads to less angiotensin II and, hence, less aldosterone and, hence, less reabsorption of water, increasing urine output.
Renin activates RAAS, leading to the production of aldosterone, which increases reabsorption of water. Therefore, increased renin secretion would decrease urine output.
Decreased ADH secretion means less water is reabsorbed, leading to increased urine output.
ANF increases urine output by promoting natriuresis (sodium excretion) and diuresis. Therefore, increased secretion of ANF would increase urine output.

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