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Q.

Which of the following would decrease GFR?

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a

Decreased hydrostatic pressure in Bowman’s capsular space

b

Dilation of afferent arteriole

c

Dilation of efferent arteriole

d

Decreased plasma protein concentration in glomerular capillaries

answer is D.

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Detailed Solution

Glomerular capillary pressure is regulated by the ratio of upstream (afferent arteriole) and downstream (efferent arteriole) resistance to flow. Dilation of the afferent arteriole (choice C) will increase glomerular capillary pressure and increase filtration, whereas dilation of the efferent arteriole (choice D) will decrease the pressure and thus decrease filtration.

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Which of the following would decrease GFR?