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Q.

Which one of the following option is correct?

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a

RNA being a catalyst is  less reactive and stable

b

DNA is more reactive and less stable

c

DNA being complementary double-stranded resists changes by a process of repair

d

RNA has evolved from DNA  with chemical modifications

answer is B.

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Detailed Solution

RNA was the first genetic material. There is now enough evidence to suggest that essential life processes (such as metabolism, translation, splicing, etc.), evolved around RNA. Presence of free-OH at 2nd  Position in RNA, it is a reactive group and makes RNA labile and easily degradable. RNA is also now known to be catalytic, hence reactive. Therefore, DNA chemically is less reactive and structurally more stable when compared to RNA,  presence of thymine at the place of uracil also confers additional stability to DNA.

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