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Q.

Which technique among the following, is most appropriate in separation of mixture of 100 mg of p-nitrophenol and picric acid? 

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a

Sublimation

b

Steam distillation

c

Preparative TLC (Thin Layer Chromatography)

d

2-5 ft long column of silica gel

answer is D.

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Detailed Solution

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Preparative thin-layer Chromatography separates compounds on a macro scale (0.05-1) by using a thick layer of adsorbent (0.5-5) mm.

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