Q.

Choose the Correct one with respect to double stranded DNA structure.

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a

Each strand of DNA has its adjacent nucleotides joined by 5ʹ → 5ʹ phosphodiester bonding.

b

Each strand of DNA has its adjacent nucleotides joined by 3ʹ → 5ʹ phosphodiester bonding.

c

Each strand of DNA has its adjacent nucleotides joined by 5ʹ → 3ʹ phosphodiester bonding.

d

Each strand of DNA has its adjacent nucleotides joined by 3ʹ → 3ʹ phosphodiester bonding.

answer is B.

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Detailed Solution

When a nucleotide is joined to already present nucleotide during DNA replication, the phosphate attached to 5th carbon of sugar of incoming nucleotide is attached at the 3rd carbon of sugar of earlier nucleotide and the phosphodiester bonding polarity is described as 3ʹ → 5ʹ
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