First slide

The Search for Genetic Material

Question

Choose the correct statement with respect to works of Oswald Avery, Colin MacLeod and Maclyn McCarty.

Easy

A

Protein digesting enzymes did affect transformation
B

RNA digesting enzymes did affect transformation
C

DNA digesting enzymes did not affect transformation
D

The transforming substance was neither RNA nor Protein

Solution

Avery et.al worked to determine the biochemical nature of transforming principle in Griffith’s experiments. They purified the biochemicals of heat killed S-strain of Streptococcus pneumoniae to understand which one was responsible for transforming R cells to S cells. They found proteases, RNases did not affect transformation and only DNase could affect transformation (R strain not converted to S strain).

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