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a
An enzyme has either one or more than one polypeptide chains.
b
Cofactors make the enzymes catalytically active.
c
A metallic ion cofactor forms coordination bonds with only substrate but not with the apoenzyme.
d
Haeme is the cofactor of peroxidase which is tightly bound to the apoenzyme and is a part of active site of enzyme.
answer is C.
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