First slide

Regulation of Gene Expression

Question

In E. coli, the lac operon gets switched on when

Easy

A

lactose is present and it binds to the repressor
B

repressor binds to operator
C

RNA polymerase binds to the operator
D

lactose is present and it binds to RNA polymerase

Solution

When lactose is present, it act as an inducer and binds to the repressor and inactivates it. This repressor fails to bind to operator. Therefore, the RNA polymerase binds to the promoter and transcript mRNA thus switching on the lac operon and allowing transcription to proceed.

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