Q.

The enzyme pyruvate dehydrogenase helps in conversion of

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a

Pyruvic acid to acetyl coenzyme A in the cytosol

b

Pyruvic acid to acetyl coenzyme A in the peri-mitochondrial space

c

Pyruvic acid to acetyl coenzyme A in the mitochondrial matrix

d

Pyruvic acid to acetyl coenzyme A in the stroma of chloroplast

answer is C.

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Detailed Solution

Pyruvate, which is formed by the glycolytic catabolism of carbohydrates in the cytosol, after it enters mitochondrial matrix undergoes oxidative decarboxylation to form acetyl CoA by a complex set of reactions catalysed by pyruvic dehydrogenase. The reactions catalysed by pyruvic dehydrogenase require the participation of several coenzymes, including NAD+ and Coenzyme A.Pyruvic acid + CoA+ NAD+→Pyruvate dehydrogense, Mg+ Acetyl CoA+ CO2+NADH+H+
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