First slide
Regulation of Gene Expression
Question

How many of the following statements are true?
(i) 6 turns of B-DNA has 120 nucleotides.
(ii) In prokaryotes, gene regulation generally occurs at transcriptional level.
(iii) Operon concept was given by Jacob and Monod while working on yeast.
(iv) The enzyme required for peptide chain synthesis is a ribozyme in bacteria and lies in 50S subunit.
(v) A small segment of RNA synthesized during replication of DNA is “Okazaki segment”.

Easy
Solution

1 turn of B DNA has 10bp. Therefore, 6 turns of B-DNA has 60bp or 120 nucleotides.
In prokaryotes, control of the rate of transcriptional initiation is the predominant site for control of gene expression.
Geneticist, Francois Jacob and a biochemist, Jacque Monod first to elucidated operon concept in E.coli.
23S rRNA present in 50S subunit of ribosome in bacteria is the enzyme- ribozyme which is used for the formation of peptide bond.
A small segment of RNA synthesized during replication of DNA is called the primer.

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