Identify the biocatalyst that helps in obtaining the connecting link between glycolysis and Kreb’s cycle.
Pyruvate, which is formed by the glycolytic catabolism of carbohydrates in the cytosol, after it enters mitochondrial matrix undergoes oxidative decarboxylation by a complex set of reactions catalysed by pyruvic dehydrogenase. During this process, two molecules of NADH and two molecules of acetyl CoA are produced from the metabolism of two molecules of pyruvic acid. The acetyl CoA then enters a cyclic pathway, tricarboxylic acid cycle, more commonly called as Krebs’ cycle.