Identify the correct statement w.r.t. capping.

Easy

A

Found exclusively in prokaryotes.
B

During capping 50 to 250 adenine nucleotides are added at the 3' end.
C

The presence of a 5' cap decreases the stability of mRNA and influences the removal of introns.
D

It involves addition of an extra nucleotide at the 5' end of the mRNA and methylation by the addition of a methyl group to the base in the newly added nucleotide.

Solution

Almost all eukaryotic pre-mRNAs are modified at their 5' ends by the addition of a structure called a 5' cap. This capping consists of the addition of an extra nucleotide at the 5' end of the mRNA and methylation by the addition of a methyl group (CH₃) to the base in the newly added nucleotide and to the 2' –OH group of the sugar of one or more nucleotides at the 5' end.

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