The main difference between diffusion and facilitated diffusion is

Easy

A

diffusion takes place down the concentration gradient and facilitated diffusion is against concentration gradient.
B

diffusion utilizes no metabolic energy and facilitated diffusion uses metabolic energy
C

diffusion is non-specific and facilitated diffusion is specific.
D

diffusion requires a protein and facilitated diffusion does not require any proteins.

Solution

Diffusion does not require any protein but facilitated diffusion takes place through a protein. Facilitated diffusion is specific and diffusion is not specific. Both are passive processes and occur down the concentration gradient without using metabolic energy. Hormones and inhibitors influence the facilitated diffusion but not diffusion.

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