Malic acid inhibits the activity of enzyme succinate dehydrogenase. During this inhibition
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a
Vmax increases, Km decreases
b
Vmax remains the same, Km decreases
c
Vmax decrease, Km increases
d
Vmax remains the same, Km increases
answer is D.
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Detailed Solution
Inhibition of succinic dehydrogenase by malonate is an example of competitive inhibition. Malonate closely resembles the substrate succinate in structure. In competitive inhibition V max remains the same and Km increases.