First slide

Enzymes

Question

Malonic acid is a competitive inhibitor of an enzyme of Krebs cycle. Malonic acid structurally resembles one of the following.

Easy

A

Malic acid
B

Succinate dehydrogenase
C

Fumaric acid
D

Succinic acid

Solution

Malonic acid is a competitive inhibitor of succinate dehydrogenase. In structure, it resembles Succinic acid which is the substrate for Succinic acid dehydrogenase. This enzyme is present in the inner membrane of mitochondrion.

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