Match Column I with Column II
Column I Column II
a. Missense mutation i. Changes a sense codon into a synonymous codon, leaving unchanged the amino acid sequence of the protein
b. Nonsense mutation ii. Changes a sense codon into a different sense codon, resulting in the incorporation of a different amino acid in the protein
c. Silent mutation iii. Changes a mutant phenotype back to the wild-type phenotype
d. Reverse mutation iv. Changes a sense codon into a nonsense codon, causing premature termination of translation

	Column I		Column II
a.	Missense mutation	i.	Changes a sense codon into a synonymous codon, leaving unchanged the amino acid sequence of the protein
b.	Nonsense mutation	ii.	Changes a sense codon into a different sense codon, resulting in the incorporation of a different amino acid in the protein
c.	Silent mutation	iii.	Changes a mutant phenotype back to the wild-type phenotype
d.	Reverse mutation	iv.	Changes a sense codon into a nonsense codon, causing premature termination of translation

Moderate

Solution

Missense mutation Changes a sense codon into a different sense codon, resulting in the incorporation of a different amino acid in the protein
Nonsense mutation Changes a sense codon into a nonsense codon, causing premature termination of translation
Silent mutation Changes a sense codon into a synonymous codon, leaving unchanged the amino acid sequence of the protein
Reverse mutation Changes a mutant phenotype back to the wild-type phenotype

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