First slide

Enzymes

Question

Metal ion forming coordination bonds in active site carboxypeptidase and its substrate is

Easy

A

${Mg}^{2 +}$
B

${Zn}^{2 +}$
C

$K^{+}$
D

${Mn}^{2 +}$

Solution

A number of enzymes require metal ions for their activity which form coordination bonds with side chains at the active site and at the same time form one or more coordination bonds with the substrate, e.g., zinc is a cofactor for the proteolytic enzyme carboxypeptidase.

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