Genetic Code
Question
A mRNA has the sequence of nucleotides in its translated region from 5' to 3' as AUGGGACGAUGGUGA. Due to mutation, if the 7th base Cytosine is replaced by Uracil, what are the amino acids present in a sequence in the formed oligopeptide.?
Moderate
Solution
AUG is the codon for Methionine
GGU, GGC, GGA and GGG are the codons for Glycine.
Arginine has codons CGU, CGC, CGA, CGG, AGA and AGG
Tryptophan has only one codon UGG.
If the 7th base Cytosine is changed to Uracil, then the codon CGA is changed to UGA, which is a non-sense codon. Hence the there is formation of dipeptide with amino acids Methionine and Glycine only.
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