First slide

Regulation of Gene Expression

Question

In negative operon

Easy

A

co-repressor binds with repressor.
B

co-repressor does not bind with repressor.
C

co-repressor binds with inducer.
D

cAMP have negative effect on lac operon.

Solution

During negative control, i.e., during the presence of tryptophan some molecules of tryptophan act as co-repressor, co-repressor-bind with inactive repressor. Co-repressor repressor complex bind with-operator region and prevent the binding of RNA polymerase to the promoter and the trp-operon is off.

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