First slide

Aerobic Respiration

Question

The number of decarboxylations that occur in one turn of citric acid cycle is:

Easy

A

Two
B

Three
C

Four
D

Six

Solution

In Krebs cycle there is two successive steps of decarboxylation, leading to the formation of α-ketoglutaric acid and then succinyl-CoA. The conversions are as follows
Isocitrate (6C) →α-ketoglutarate (5C) + ${CO}_{2}$
α-ketoglutarate (5C) → Succinyl CoA(4C) + ${CO}_{2}$

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