First slide

Biotechnological Applications in Agriculture

Question

In order to protect cotton plants from insect infection, mode of action of Bt toxin is:

Easy

A

midgut cell lysis and swelling
B

paralysis and loss of coordination
C

formation of abnormal proteins
D

brain death

Solution

Once an insect ingest the inactive Bt toxin, it is converted into an active form of toxin due to the alkaline pH of the gut which solubilise the crystals. The activated toxin binds to the surface of midgut epithelial cells and create pores that cause cell swelling and lysis and eventually cause death of the insect.

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