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Questions  

Oxidative decarboxylation is observed in which step of aerobic respiration?

a
Conversion of oxaloacetic acid to citric acid
b
Conversion of succinic acid to fumaric acid
c
Conversion of phosphoenolpyruvate to pyruvic acid
d
Conversion of pyruvic acid to acetyl CoA

detailed solution

Correct option is D

Pyruvate, which is formed by the glycolytic catabolism of carbohydrates in the cytosol, after it enters mitochondrial matrix undergoes oxidative decarboxylation by a complex set of reactions catalysed by pyruvic dehydrogenase. The reactions catalysed by pyruvic dehydrogenase require the participation of several coenzymes, including NAD+ and Coenzyme A.Pyruvic acid+CoA+NAD+→Pyruvate dehydrogenaseMg2Acetyl CoA+CO2+NADH+H+

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Similar Questions

Link reaction
a. occurs in mitochondrial matrix
b. is catalysed by dehydrogenase enzyme
c. involves oxidative decarboxylation and oxidative phosphorylation
   Choose the correct one(s). 


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